Past Calls

Past calls for proposals include:

  1. Singapore Bioimaging Consortium (SBIC) 3rd Grant Call (2007) - Results
  2. Joint SBIC - SSCC Grant Call (2007) - Results
  3. BMRC - NMRC Joint Grant Call (2007) - Results
  4. Singapore Immunology Network (SigN) Grant Call (2007) - Results
  5. Singapore Immunology Network (SIgN) Grant Call (2006) - Results
  6. Singapore Bioimaging Consortium (SBIC) 2nd Grant Call (2006) - Results
  7. BMRC - NMRC Joint Grant Call (2006) - Results
  8. Singapore Stem Cell Consortium (SSCC) Grant Call (2006) - Results
  9. Singapore Bioimaging Consortium (SBIC) 1st Grant Call (2005) - Results
  10. BMRC 4th Grant Call (2005) - Results
  11. BMRC 3rd Grant Call (2004) - Results
  12. BMRC - JDRF Joint Grant Call (2004) - Results
  13. SARS Grant Call (2003) - Results

SINGAPORE BIOIMAGING CONSORTIUM (SBIC) 3RD GRANT CALL (2007)

Theme: Applications of Novel Technologies & Imaging Modalities in Medical & Biological Imaging

RESULTS

Project Title

Host Institution

Network Director
The development of structural and fluorescence imaging of cells and tissue at sub 50nm resolutions

National University of Singapore

Prof Frank Watt

Investigation on Cancer using Terahertz Spectroscopy and Imaging

National Cancer Centre
Dr Malini Olivo

 

 

JOINT SBIC-SSCC GRANT CALL (2007)

Theme: Bioimaging on Stem Cells

RESULTS

S/N

Project Title

Host Institution

Network Director
1

Application of bioimaging techniques, including FRET, FCS and FLIM, to investigate the differentiation of embryonic and neural stem cells
Institute of Medical Biology

Assoc Prof Sohail Ahmed

2

Establishment of a novel cellular electron tomography technology for in vivo imaging of neural stem cell development and function by nanogold labeled markers at nanometer scale

National University of Singapore
Asst Prof He Wanzhong
 
3

Novel insight into basic problems of stem cell biology through live imaging of neuronal stem cells in-vitro and in vivo using Focal Modulation Microscopy

National University of Singapore

Prof Colin Sheppard

 
4

Stem cell transplantation for heart repair: non-invasive monitoring of cellular grafts and heart function
Institute of Medical Biology

Dr Robert Zweigerdt

 
5

The challenge of real-time imaging of signaling pathways in embryonic stem cells: is mES cell pluripotency related to cadherin signaling and their epithelial-like behaviour?
Institute of Medical Biology

Dr Ed Manser

 
6

Imaging of Transplanted Bone Marrow Derived Stem Cells (BMSCs) by MRI in Chondral Defect, Meniscus Injury and Diabetic Neuropathy - An Animal Study

National University of Singapore
Assoc Prof James Hui Hoi Po
 

 

 

-NMRC JOINT GRANT CALL (2007)

RESULTS

S/N
Title
Host Inst
PI
1
Comparative Studies of the Structure and Adhesion Properties of the aLß2, aMß2, aXß2 integrins, and the crystallographic studies of the ß2 and ß3 integrins.
 NTU Alex Law
2
 Malaysia-Singapore ALL 2007 Study - A Risk-Stratified Multi-Centre Childhood Acute Lymphoblastic Leukaemia Study Incorporating Pharmacokinetics/ Pharmacodynamic Study of Vincristine NUS Allen Yeoh Eng Juh
3
 Assessment and Training System for Micromanipulation Tasks in Surgery NTU Ang Wei Tech
4
 Development and Validation of a New Rapid Method for Detection of Drug Resistance in Mycobacterium Tuberculosis NCC Ann Lee Siew Gek
5
 C. elegans as a Model System for the Investigation of Mitochondrial DNA Mutations in Ageing. NUS Barry Halliwell
6
 Regulation of Intracellular pH, a Novel Mechanism for the Cardioprotection Induced by Hydrogen Sulfide NUS Bian Jinsong
7
 Manipulating the Reactive Oxygen Species (ROS) Status as a Novel Therapeutic Strategy in Eliminating Cancer Stem Cells in Human Adult Malignant Glioma NNI Carol Tang
8
 Functional Roles of Ff1b in the Embryonic Development and Maintenance of the Zebrafish Interrenal NUS Chan Woon Khiong
9
 Gene-silencing Fibrous Scaffolds for Regenerative Medicine NTU Chew Sing Yian
10
 Medakafish as a Model for Human Bone Disorders: The Role of Osterix and SOST in Controlling Bone homeostasis NUS Christoph Winkler
11
 Interplay of Centrins in Co-ordination of Organelle Biogenesis and Cell Division in Trypanosoma brucei NUS Cynthia He Yingxin
12
 Investigating the Role of SLC4A11 Gene in the Corneal Endothelium in Health and Disease Using RNA Interference (RNAi). SERI Eranga Vithana
13
 The Role of the Nucleus Incertus in Antipsychotic Drug-induced Weight Gain NUS Gavin Stewart Dawe
14
 Characterization Of Isthmin, A Novel Secreted Antiangiogenic Protein In Cancer and Embryonic Development NUS Ge Ruowen
15
 Functional Investigation of Liver Tumor Regulated Genes and Generation of Transgenic Liver Tumor Models in Zebrafish NUS Gong Zhiyuan
16
 Genetic and Functional Analysis of Gastrokine 1: A Novel Candidate Biomarker for Gastric Cancer NCC Ho Meng Fatt
17
 Development of a Functional Tissue-Engineered Bone-Ligament-Bone Graft with Novel Fixation Device to Bone Tunnels for ACL Reconstruction NUS James Goh Cho Hong
18
 Exploring the Structure and Function of Trans-encoded MHC's NUS Kim Chu Young
19
 The Regulation of Actin Cytoskeleton and Cellular Functions by POPX2 and its Partners NTU Koh Cheng Gee
20
 Crystal Structure Determination and Functional Characterization of Two Oncogenic Kinases, NPM/ALK and BRK, Involved in Malignant Transformation of T and B Lymphocytes in Lymphoma NUS Kunchithapadam Swaminathan
21
 Synthesis of Nitrogen-containing Heterocycles as Potential Therapeutic Agents for the Management of Central Nervous System Disorders NUS Lam Yulin
22
 Generating A High Quality Immortal Mesenchymal Stem Cell Line for Chondrogenesis NUS Lee Eng Hin
23
 The Ex Vivo Expansion of Umbilical Cord Stem Cells for Ocular Surface Tissue Regeneration SNEC Leonard Ang Pek Kiang
24
 Studies of a Novel Secretion System (T6SS) of Aeromonas hydrophila and Edwardsiella tarda and Therapeutics Applications to Disarm Pathogens NUS Leung Ka Yin
25
 Novel Tyrosine Kinase Substrates of Oncogenic EGFR Signaling NUS Lim Yoon Pin
26
 Regulation of T cell Development by Annexin-1: Importance in the Development of Asthma NUS Lina Lim Hsiu Kim
27
 Functional Characterization of BNIP-H (Caytaxin) and its Novel Cellular Targets in Regulating Neuritogenesis and Production of Neurotransmitters NUS Low Boon Chuan
28
 Exploring DNA-Cleaving Activities of Varacin C and its Analogues and their Potential Uses in Cancer Therapy NUS Lu Yixin
29
 New anticoagulants from Snake Venoms: Structure-Function Relationships and Mechanisms of Action NUS Manjunatha Ramachandra Rao Kini
30
 Understanding Roles of Anaphase-Promoting Complex (APC) in Acute Myeloid Leukemia (AML) development NUS Marito Araki
31
 MicroRNA Processing and Enhancer Function in the Control of Hox Gene Expression NTU Mark Featherstone
32
 Phagosome Lipidomics and Autoimmunity Associated with FcgRIIb Polymorphism in Humans NUS Markus R Wenk
33
 Characterization of Genetic and Epigenetic Mechanisms tha Regulate Cachectic Muscle Wasting NUS Mridula Sharma
34
 Enabling Phosphoproteome Analysis with Mass Spectrometry in Elucidating Signalling Pathways in Cancer and Immunity NTU Newman Sze Siu Kwan
35
 Mycobacterial Versus Human HSP70: A Detailed Comparison of their Immunological Activities. NUS Paul A. MacAry
36
 Unravelling the Functional Roles of IL-13Ra2 in Promoting the Tumorigenesis of Human Gliomas NCC Paula Lam Yeng Po
37
 Regulation of the TAK1 and MEKK3 Protein Kinases in the Inflammatory Response. NTU Peter Cheung
38
 Biochemical and Functional Analysis of the Newly Discovered DNA (dRP) Lyase Activity of Proto-oncoproteins HMGA: Implications for Genome Stability in Human Neoplasias and Stem Cells. NTU Peter Droge
39
 Understanding the Functional Role of the STEVOR Multigene Family in the Human Parasite Plasmodium falciparum NTU Peter Rainer Preiser
40
 Interaction of Quadruplex DNA with Proteins and Small Molecules NTU Phan Anh Tuan
41
 Nuclear Phosphoinositide Signaling and Chromatin Remodelling Factors and their role in Cancer NCC Philip Karuman
42
 Development and In-vivo Evaluation of SUWA Tissue Engineered Esophagus NTU Sandy Chian Kerm Sin
43
 Cyclin Dependent Kinase 5 Phosphorylation of dCatenin: Implications in Synaptic Organisation and Function in Neurodevelopment and Neurodegeneration. NUS Sashi Kesavapany
44
 Project to Study the Effect of Bcl-2 Expression on Mitochondrial Physiology in Tumor Cells NUS Shazib Pervaiz
45
 Structural and Functional Characterization of Ribosome Modifying Methyltransferases that Confer Antibiotic Resistance in Disease Causing Microorganisms NUS Sivaraman Jayaraman
46
 Iron Transporter, DMT1, Transgenic Mouse Model of Oxidative Stress: Implications in Parkinson's Disease NUS Soong Tuck Wah
47
 The Role of Interferon Regulatory Factors in Regulating the Expression of NKG2D Ligands NUS Stephan Gasser
48
 The Role of Polycomb Group Protein Ezh2 in Immune Response of Dendritic Cells NTU Su I Hsin
49
 Transplantation of a Prefabricated Neovascularised Segmental Pancreas into a Diabetic Rat Recipient SGH Tan Bien Keem
50
 The Development of Selective Inhibitors based on the Structural and Mechanistic Studies of Cystathionine-g-lyase (CSE) NUS Tan Choon Hong
51
 In Vivo Vascularization and Maturation of Bioartificial Grafts for Organ Restoration NUS Theodoros Kofidis
52
 Characterization of Mechanisms through which Cullin-based E3 Ubiquitin Ligases are Regulated in Health and Disease NUS Thilo Hagen
53
 Mechanistic Studies of Epidermal Growth Factor Receptor and Cdc42 Signalling in vivo Using Fluorescence Spectroscopy Techniques. NUS Thorsten Wohland
54
 Contribution of Lymphatic Function in Atherosclerosis and its Modulation by Lipid Mediators NUS Veronique Angeli
55
 Combined Modality Chemo-antiangiogenic Therapy for Brain Tumor through Functional Sustained-Released Depots and in vivo microPET Imaging NUS Wang Chi Hwa
56
 Hydrogen Bonding Interaction Between Antibiotics and Peptide Precursors on Bacterial Surfaces: An Investigation using Single-Molecule Fluorescence Detection Techniques NTU Xing Bengang
57
 Structural, Dynamic and Functional Insights into RNA Helicase Dbp5 Involved in the Life Cycle of RNA NUS Yang Daiwen
58
 Molecular Mechanisms of Action and Human Bioaccumulation of a Novel Estrogenic Compound Secreted by a Singapore Phytoplankton Isolate, Chattonella marina. NUS Yong Eu Leong
59
 Epigenetic Regulation of Gene Expression in Human Malaria Parasites Plasmodium falciparum; New Target for Malaria Drug Development NTU Zbynek Bozdech
60
 Dissecting the ERp29-mediated Downstream Modulators and its Oncogenic Role in Breast Tumour Progression NUS Zhang Daohai
61
 Use of NIR-to-visible Upconversion Fluorescent Nanoparticles for Synergistic Non-invasive Imaging and Photodynamic Therapy of Cancer in Deep Tissues NUS Zhang Yong

 

 

SINGAPORE IMMUNOLOGY NETWORK (SIgN) 2007 GRANT CALL

RESULTS

S/N
Project Title
Host Institution
Network Director
1
 Novel T cell-derived factor induces robust dendritic cell maturation- search for new adjuvants
Nanyang Technological University (NTU)
Christiane Ruedl
2
A Study on Mouse and Human Tumor Initiation and Growth by Annexin-A1: Its Role in Tumor Immune Evasion
National University of Singapore (NUS)
Lim Hsiu Kim Lina
3
Molecular epidemiology, immune monitoring and the development of a vaccine platform for Chikungunya
Environmental Health Institute (EHI)
Ng Lee Ching
4

Development of malaria antigen library: a tool for identification of correlates of protection use for identification of human correlates of protection
Nanyang Technological University (NTU)
Peter Preiser
5
Role of NK Cells and NKG2D in Chemotherapy of Cancer
National University of Singapore (NUS)
Stephen Gasser
6

Polarized Innate Immune Response in Minimal Change Nephrotic Syndrome (MCNS) - A Systems Approach to Define the Molecular Basis of Pathogenesis
National University of Singapore (NUS)
Yap Hui Kim
Renewal
1
The Development of TCR-Like monoclonal antibodies with specificity for Epstein-Barr virus infected cells.
National University of Singapore (NUS)
Paul MacAry